Status:

COMPLETED

Inflammatory Indices in Predicting the Failure of Inhaled Corticosteroids Reduction in Young Participants With Asthma

Lead Sponsor:

National Institute for Tuberculosis and Lung Diseases, Poland

Collaborating Sponsors:

University of Rzeszow

The Regional Public Hospital in Lesko, Poland

Conditions:

Asthma Chronic

Eligibility:

All Genders

12-18 years

Phase:

NA

Brief Summary

A prospective, observational, interventional, single-blind study (blinded for a clinician in the field of inflammatory parameters). The aim of the study is evaluation of the usefulness of induced spu...

Detailed Description

Introduction Guidelines for the treatment of asthma recommend the use of the smallest dose of inhaled steroid (ICS), which allows to maintain control of the symptoms of the disease. The GINA 2006 guid...

Eligibility Criteria

Inclusion

  • mild or moderate asthma with a stable course of at least 3 months:
  • symptoms less than 4x per week,
  • use of SABA below 3x a week,
  • night awakening below 1x per week,
  • FEV1\> 80% of predicted
  • no dose change in ICS or use of systemic steroids from 3 months
  • good adherence to treatment

Exclusion

  • infection or exacerbation of asthma requiring the use of systemic steroids (or changes in the dose of inhaled steroids) in the last 3 months before the study
  • other chronic lung diseases or general diseases affecting the respiratory system
  • tobacco smoking
  • FEV1 below 80% of the predicted value

Key Trial Info

Start Date :

February 1 2016

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 31 2019

Estimated Enrollment :

58 Patients enrolled

Trial Details

Trial ID

NCT03788057

Start Date

February 1 2016

End Date

March 31 2019

Last Update

September 19 2024

Active Locations (1)

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The Regional Public Hospital in Lesko, Poland

Lesko, Poland, 38-600