Status:
UNKNOWN
Effects of Dienogest and Dienogest Plus Estradiol Valerate in Ovarian Endometrioma
Lead Sponsor:
Bagcilar Training and Research Hospital
Collaborating Sponsors:
Kocaeli Derince Education and Research Hospital
Suleymaniye Birth And Women's Health Education And Research Hospital
Conditions:
Ovarian Reserve
Eligibility:
FEMALE
18-40 years
Phase:
PHASE4
Brief Summary
Progesterone resistance in endometriosis is a known fact. The progestin derivatives used in endometriosis cause decidualization and atrophy of ectopic foci. Moreover, they inhibit neo-angiogenesis, pr...
Eligibility Criteria
Inclusion
- Study Group: At least one endometrioma greater than 3 cm, between 18-40 years of age, without surgical indication at the time of diagnosis, occasionally and intermittently controlled pain with NSAIDs or no pain symptom
- Control Group: Patients with reproductive age without any ovarian cysts
Exclusion
- suspicion of malignancy, irregular mentrual period, endocrine diseases, drug intake that may affect ovarian reserve in the last 6 months (i.e GnRH agonists), previous ovarian surgery, AMH levels under 2 ng/ml.
Key Trial Info
Start Date :
January 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2019
Estimated Enrollment :
710 Patients enrolled
Trial Details
Trial ID
NCT03789123
Start Date
January 1 2019
End Date
December 1 2019
Last Update
December 28 2018
Active Locations (1)
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1
Tolga Karacan
Istanbul, Bagcilar, Turkey (Türkiye), 34100