Status:
TERMINATED
Focal Intraoperative Radiotherapy of Brain Metastases
Lead Sponsor:
AC Camargo Cancer Center
Collaborating Sponsors:
Carl Zeiss Meditec AG
Conditions:
Brain Metastases, Adult
Central Nervous System Metastases
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
Brain metastases (BM) are the most prevalent tumors of the central nervous system (CNS), with a ratio of 10: 1 in relation to primary tumors. In prospective studies, whole-brain radiotherapy (WBRT) re...
Detailed Description
Brain metastases (BM) are the most prevalent tumors of the central nervous system (CNS), with a ratio of 10: 1 in relation to primary tumors. This type of metastasis occurs in 20-40% of cancer patient...
Eligibility Criteria
Inclusion
- Age \>18 years
- Histologically confirmed diagnosis of invasive cancer in the presence of up to 10 lesions suggestive of BM
- Indication of resection of single lesion suggestive of BM and evidence of macroscopic complete resection
- Patient consent to participate in the study
Exclusion
- Previous cranial radiotherapy
- Any kind of antineoplasic systemic treatment for less than 7 days of the procedure
- Cavities with proximity \< 10 mm from the brainstem or optical pathway.
- Pregnant patients
Key Trial Info
Start Date :
May 2 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 30 2022
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT03789149
Start Date
May 2 2019
End Date
June 30 2022
Last Update
July 27 2023
Active Locations (1)
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1
AC Camargo Cancer Center
São Paulo, São Paulo, Brazil, 01509-900