Status:

COMPLETED

Population-based Study in Screening for Liver Fibrosis

Lead Sponsor:

Judit Pich Martínez

Conditions:

Liver Diseases

Eligibility:

All Genders

40+ years

Brief Summary

Study to assess the prevalence of significant liver fibrosis in general population using Transient Elastography

Detailed Description

This is a population-based study. Subjects will attend a primary care center where a physical examination, general blood test and transient elastography will be carried out. Only the group of patients...

Eligibility Criteria

Inclusion

  • Age ≥ 40 years
  • Able to give informed consent

Exclusion

  • Previously known chronic liver disease (including cholestasis). Patients with already known liver steatosis but no diagnosis of liver fibrosis or cirrhosis can be included
  • Subjects with mental incapacity, language barrier, insufficient social support or any other reason considered by the investigator precluding adequate understanding or cooperation in the study
  • Subjects with a history of current malignancy including solid tumors and hematologic disorders
  • Subjects with significant extrahepatic disease that may impair short-term prognosis (including congestive heart failure New York Heart Association Grade IV, COPD GOLD \>3)
  • Subjects with kidney disease (serum creatinine \>3mg/dL or under renal replacement therapy)

Key Trial Info

Start Date :

March 19 2018

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

January 7 2025

Estimated Enrollment :

30000 Patients enrolled

Trial Details

Trial ID

NCT03789825

Start Date

March 19 2018

End Date

January 7 2025

Last Update

January 17 2025

Active Locations (45)

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Page 1 of 12 (45 locations)

1

Dubrava Hospital

Zagreb, Croatia, 10000

2

Poliklinika Croatia

Zagreb, Croatia, 1000

3

Odense University Hospital

Odense, Denmark

4

Centre de santé Municipal Etienne Gatineau-Sailliant de Genevilliers

Gennevilliers, France, 92230