Status:
UNKNOWN
RCA for CRRT in Liver Failure and High Risk Bleeding Patients
Lead Sponsor:
Air Force Military Medical University, China
Conditions:
Liver Failure
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this single center, randomized, control, open-labeled study is to evaluate the effect and safety of RCA versus no anticoagulation for CRRT in patients with liver failure and high risk b...
Detailed Description
Liver failure (LF) is a common co-morbidity in critical care patients who need continuous renal replacement therapy (CRRT). Patients with LF are usually associated with impaired coagulation, impaired ...
Eligibility Criteria
Inclusion
- Liver failure (acute liver failure and chronic liver failure)
- High bleeding risk
- Scheduled CRRT treatment
- Informed consent
Exclusion
- Use of other anticoagulants
- Uncorrectable hypoxemia (PaO2 \< 60 mmHg) or systemic hypoperfusion shock
- Pregnancy or lactation
- Fistula, CRRT treatment time \< 12 hours
Key Trial Info
Start Date :
September 6 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 30 2021
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT03791190
Start Date
September 6 2018
End Date
August 30 2021
Last Update
January 3 2019
Active Locations (1)
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1
Xijing Hospital of Nephrology
Xi'an, Shaanxi, China, 710032