Status:
UNKNOWN
The Th9/IL-9 and Early Enteral Nutrition in Sepsis
Lead Sponsor:
Nanjing First Hospital, Nanjing Medical University
Conditions:
Sepsis
Intestinal Mucosal Barrier
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
The investigators aim to evaluate the roles of Th9/IL-9 in the mechanisms of early enteral nutrition (EEN) maintaining intestinal mucosal barrier in sepsis. The results of this study would lay the fou...
Eligibility Criteria
Inclusion
- Clinical diagnosis of sepsis
- Within 3 days of sepsis onset before ICU admission
- No artificial nutrition (enteral or parenteral nutrition) were provided before ICU admission
Exclusion
- Ileus
- Digestive tract hemorrhage
- Inflammatory bowel disease
- Abdominal hypertension (IAP \>25mmHg)
- Cancer or chronic organ dysfunction (e.g., hepatic or renal dysfunction)
- Malnutrition or immunodeficiency
- Long-term use of hormones
Key Trial Info
Start Date :
October 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 30 2020
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT03791866
Start Date
October 1 2018
End Date
June 30 2020
Last Update
January 3 2019
Active Locations (1)
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1
Nanjing First Hospital
Nanjing, Jiangsu, China, 210000