Status:

UNKNOWN

Personality, as a Predictive Factor of Therapeutic Response on Quality of Life After Continuous Perfusion of Dopaminergic Drugs, in Parkinson's Disease

Lead Sponsor:

University Hospital, Toulouse

Conditions:

Parkinson Disease

Eligibility:

All Genders

18+ years

Brief Summary

The aim of the study is to evaluate if patients' personality could be considerate as predictive factor of quality of life after the establishment of continuous infusion of dopaminergic treatments to o...

Detailed Description

Parkinson's disease leads to quality of life degradation, especially at level of motor complications. Second line treatment can be proposed to patients. There are deep brain stimulation and two treatm...

Eligibility Criteria

Inclusion

  • Patients having Parkinson's disease according to United Kingdom Parkinson's Disease Society Brain Bank (UKPDSBB) criteria
  • All Parkinson's patients presenting motor fluctuations and/or disabling dyskinesia and in need of the establishment of a second line treatment by subcutaneous apomorphine infusion or intrajejunal infusion of levodopa-carbidopa in the context of classical care of their Parkinson's disease
  • Patient able to give its free and informed consent
  • Patient having a social security

Exclusion

  • Patients presenting atypical Parkinson's syndrome
  • Patients having a deep brain stimulation
  • Patient having a psychiatric disease such as: mood disorders, psychotic disorder…
  • Patients presenting a cognitive decline evaluated by a Montreal Cognitive Assessment (MoCA) score inferior to 24
  • None ability to give its consent
  • Patients unable to realize the tests provided in the context of this study
  • Patients under supervision, curators, or legal guardian
  • Patients non-affiliated to a social security
  • Patients in exclusion period of another study.

Key Trial Info

Start Date :

December 18 2018

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 18 2021

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT03793491

Start Date

December 18 2018

End Date

June 18 2021

Last Update

January 4 2019

Active Locations (1)

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1

UHToulouse

Toulouse, France, 31000