Status:
COMPLETED
Supplementation of a Leucine-enriched Protein Blend
Lead Sponsor:
McMaster University
Conditions:
Dietary Modification
Diet Habit
Eligibility:
All Genders
18-29 years
Phase:
EARLY_PHASE1
Brief Summary
It is well known that dietary protein transiently stimulates muscle protein synthesis (MPS) whereby changes in MPS in response to feeding may be regulated by specific downstream target proteins of mam...
Detailed Description
In a cross-over, randomized controlled trial, 10 healthy young participants (5 men and 5 women) will be recruited to undergo exercise resistance training randomized to habitual diet or habitual diet a...
Eligibility Criteria
Inclusion
- Be between the ages of 18-29 years (inclusive)
- Be able to maintain a habitual diet, physical activity patterns, and body mass throughout the trial
- Be in general good health
- Be able to participate in resistance training and aerobic training
- Understand the study procedures and sign this form providing informed consent to participate in the study
- Be able to consume a protein bar in the allotted time frame of 10 minutes
Exclusion
- Smoker
- Excessive alcohol consumption (more than 21 units of alcohol / week; 1 unit of alcohol is approximately 25 mL of spirits (40% alcohol), 250 mL of beer (4% alcohol) or 75 mL of wine (13% alcohol))
- Have health problems such as: renal or gastrointestinal disorders, metabolic disease, heart disease, vascular disease, rheumatoid arthritis, diabetes, poor lung function, uncontrolled blood pressure, dizziness, thyroid problems, or any other health conditions for which you are being treated that might put you at risk for this study
- Have a known or suspected allergy to local anesthetics such as lidocaine
- Have a dairy protein allergy
- Participation in another nutrition or exercise research study
- Do not understand English or have a condition the PI believes would interfere with a participants' ability to provide informed consent, comply with the study protocol, or which might confound the interpretation of the study results or put someone at undue risk
- Use of medications known to affect protein metabolism (i.e. corticosteroids, or prescription strength acne medications)
- Consuming a vegan diet
- Use of an investigational drug product or nutraceutical within the last 30 days
- Any concurrent medical, orthopedic, or psychiatric condition that, in the opinion of the Investigators, would compromise the ability to comply with the study requirements
Key Trial Info
Start Date :
June 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2020
Estimated Enrollment :
8 Patients enrolled
Trial Details
Trial ID
NCT03796897
Start Date
June 1 2019
End Date
March 1 2020
Last Update
June 20 2024
Active Locations (1)
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1
Exercise Metabolism Research Laboratory, McMaster Univeristy
Hamilton, Ontario, Canada, L8S 4K1