Status:

UNKNOWN

Daily Versus Twice Per Day Tamsulosin for Ureteral Stent Symptoms

Lead Sponsor:

Gundersen Lutheran Medical Foundation

Conditions:

Ureteral Diseases

Eligibility:

All Genders

18-70 years

Phase:

PHASE4

Brief Summary

A single-center prospective, randomized study to assess two different dosing regimens (0.4 mg QD vs. 0.4 mg BID) of tamsulosin for ureteral stent-related discomfort will be completed.

Detailed Description

Ureteral stents are commonly used to maintain patency of the ureter and are placed for several common reasons including ureteral obstruction due to nephrolithiasis, cancer, or fibrosis as well as afte...

Eligibility Criteria

Inclusion

  • Patients between the ages of 18 and 70 years old.
  • Planning to undergo ureteroscopy with ureteral stent placement at our site.
  • Able to read and understand an English language survey (USSQ).

Exclusion

  • Patients who are unable to provide informed consent.
  • Patients who are already taking an alpha-blocker.
  • Patients with hypersensitivity or known adverse side effects of tamsulosin or its ingredients and those who are not candidates for tamsulosin per attending Urologist discretion.
  • Patients with a preexisting bladder condition including UTI within 30 days of the procedure.
  • Patients with hepatitis C on boceprevir.
  • Patients who have medical conditions known to be associated with chronic pain, those taking medications for chronic pain such as gabapentin or a chronic opioid per the judgement of the PI, or those with a pain contract on file.
  • Women who are pregnant or planning to become pregnant.

Key Trial Info

Start Date :

February 18 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2021

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT03799120

Start Date

February 18 2019

End Date

December 1 2021

Last Update

February 25 2019

Active Locations (1)

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Gundersen Health System

La Crosse, Wisconsin, United States, 54601