Status:

COMPLETED

Vitamin D Supplementation for Acute Bronchiolitis

Lead Sponsor:

Mansoura University

Conditions:

Bronchiolitis

Eligibility:

All Genders

1-24 years

Phase:

PHASE2

Brief Summary

This study was conducted to evaluate the effect of oral vitamin D supplementation on the clinical course of acute bronchiolitis, and to investigate whether vitamin D deficiency among infants who requi...

Detailed Description

This is a double blind randomized controlled trial which was conducted on 60 infants who required hospital-based care for acute bronchiolitis. The patients were recruited in the period from October 20...

Eligibility Criteria

Inclusion

  • Infants aged 1-24 months of age, diagnosed clinically as acute bronchiolitis and presented with any of the following:
  • Persistent resting oxygen saturation below 92% in room air.
  • Marked tachypnea.
  • Intercostal retractions indicating respiratory distress.
  • Inability to maintain oral hydration.
  • Parent unable to care for child at home.

Exclusion

  • Infants with history of prematurity (\< 37 weeks), chronic cardiopulmonary disease, immunodeficiency, neuromuscular disease, and any other chronic medical condition.
  • Patients receiving any micronutrient supplementation or therapies containing vitamin D for 4 weeks prior to the study period.
  • Infants with previous episodes of wheezing or a physician's diagnosis of asthma.
  • Patients with acute bronchiolitis having very severe clinical score.

Key Trial Info

Start Date :

October 1 2016

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2018

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT03799406

Start Date

October 1 2016

End Date

December 1 2018

Last Update

January 11 2019

Active Locations (1)

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Mansoura University Children's Hospital

Al Mansurah, Egypt