Status:

COMPLETED

Bone Health in Patients With Atopic Dermatitis

Lead Sponsor:

Mayo Clinic

Collaborating Sponsors:

Pediatric Dermatology Research Alliance

Conditions:

Atopic Dermatitis

Eczema

Eligibility:

All Genders

5-17 years

Brief Summary

This study examines the bone health in children with atopic dermatitis

Detailed Description

The goal of this study is to objectively evaluate bone health and contributing factors in children with AD. This will be compared with existing normative data. Such an objective prospective study, dir...

Eligibility Criteria

Inclusion

  • Children 5 to 17 years of age with a diagnosis of moderate to severe atopic dermatitis as made by a dermatologist
  • Duration of atopic dermatitis symptoms for a minimum of 6 months
  • Ability to cooperate with DXA and HR-pQCT procedure

Exclusion

  • Those without a confirmed diagnosis of moderate to severe atopic dermatitis
  • Presence of concurrent disease that may also affect bone health, including rickets or other vitamin D deficiency, thyroid disease, renal disease, Paget's disease, osteogenesis imperfecta, inflammatory bowel disease, and other chronic inflammatory diseases
  • Current use of medications that may affect bone health, including bisphosphonate, Forteo, Tymlos, denosumab, thiazide, heparin, medroxyprogesterone acetate, cyclosporine, and oral tacrolimus. However, medications that are used for atopic dermatitis treatment are allowed
  • Pregnant or breast feeding females
  • Inability to cooperate with the blood draw

Key Trial Info

Start Date :

July 30 2018

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

July 16 2024

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT03800004

Start Date

July 30 2018

End Date

July 16 2024

Last Update

February 10 2025

Active Locations (1)

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Mayo Clinic

Rochester, Minnesota, United States, 55906

Bone Health in Patients With Atopic Dermatitis | DecenTrialz