Status:
COMPLETED
Effect of Macadamia Nut on Cardiometabolic Risk Factors
Lead Sponsor:
Loma Linda University
Conditions:
Cardiovascular Risk Factor
Heart Diseases
Eligibility:
All Genders
40-75 years
Phase:
NA
Brief Summary
This research study will test the effects of macadamia nuts on adiposity, and traditional and emergent risk factors of cardiometabolic disease in adult men and women
Detailed Description
Purpose of this study is to investigate the effects of Macadamia nuts on body weight, adiposity, , oxidative stress, glucose, insulin an lipid levels. it will a randomized cross over study that will i...
Eligibility Criteria
Inclusion
- Healthy men and post-menopausal women
- Overweight (BMI 25-\<40)
- Waist circumference ≥88.9 cm for women and ≥101.6 cm for men
- At least one of the following within the past year:
- Plasma triglycerides ≥150mg/dl
- Blood Pressure ≥130/85 mmHg or participants taking Antihypertensive medication
- Fasting glucose ≥100 mg/dL
- Low Density Lipoproteins\>= 130 mg/dl
Exclusion
- Nut allergy, any
- Significant chronic disease including: diabetes, congestive heart failure, renal failure, cirrhosis, or autoimmune disease
- Medications affecting lipid or glucose metabolism, immune modulators, or antibiotics in the last 6 months
- Mega-doses of lipid-lowering dietary supplements in the last 6 months
- Cancer in the last 10 years (with the exception on non-melanoma skin cancer)
- Pregnancy or lactation
- Weight change of \>10% of body weight in the last 3 months.
- Tobacco use
- Claustrophobia (may affect BOD POD testing)
Key Trial Info
Start Date :
June 24 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 25 2019
Estimated Enrollment :
38 Patients enrolled
Trial Details
Trial ID
NCT03801837
Start Date
June 24 2019
End Date
November 25 2019
Last Update
March 21 2023
Active Locations (1)
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1
Loma Linda University School of Public Health
Loma Linda, California, United States, 92350