Status:
ACTIVE_NOT_RECRUITING
A Registry for Patients With Multifocal Ground Glass Opacities (GGOs)
Lead Sponsor:
Memorial Sloan Kettering Cancer Center
Collaborating Sponsors:
M.D. Anderson Cancer Center
Brigham and Women's Hospital
Conditions:
Multiple Ground Glass Opacities (GGOs)
Eligibility:
All Genders
19+ years
Brief Summary
The purpose of this registry study is to actively monitor people with GGOs and collect information about them, so that investigators can learn more about these lesions and about the risk of developing...
Eligibility Criteria
Inclusion
- Age greater than 18 years
- Have two or more GGOs on initial CT imaging
- GGOs must be measure ≤3.0 cm and ≥0.6 cm in the greatest dimension
- GGOs must be greater than half ground glass
- A biopsy is not necessary for inclusion in the trial. Biopsy of a GGO, even with a diagnosis of adenocarcinoma, does not necessarily preclude enrollment in this surveillance protocol. In other words, patients with a diagnosis of adenocarcinoma are still eligible, at the discretion of the clinician and/or investigator, if they meet the above criteria.
Exclusion
- Patients who are actively undergoing lung cancer treatment or have a history of lung cancer, except for cases of completely resected pathologic stage IA nonsmall cell lung cancer (NSCLC). Patients with stage IA NSCLC and multiple GGOs can enroll in this active surveillance protocol after complete resection of the NSCLC and confirmation of stage on final pathologic assessment.
- The presence of any solid lesion ≥0.6 cm suspicious for malignancy.
- Patients who are actively undergoing treatment for other malignancies
Key Trial Info
Start Date :
January 9 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 1 2026
Estimated Enrollment :
338 Patients enrolled
Trial Details
Trial ID
NCT03802981
Start Date
January 9 2019
End Date
January 1 2026
Last Update
December 23 2025
Active Locations (32)
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1
University of California San Diego
San Diego, California, United States, 92103
2
Stanford University Medical Center (Data collection only)
Stanford, California, United States, 94305-5408
3
Hartford Healthcare
Hartford, Connecticut, United States, 06102
4
Rush University Medical Center (Data collection only)
Chicago, Illinois, United States, 606012