Status:
COMPLETED
Dual Ovarian Stimulation (DUOSTIM) for Poor Ovarian Responders
Lead Sponsor:
Centre Hospitalier Intercommunal Creteil
Collaborating Sponsors:
Laboratoires Genévrier
IBSA Institut Biochimique SA
Conditions:
Fertility Disorders
Eligibility:
FEMALE
20-41 years
Phase:
PHASE3
Brief Summary
During ovarian stimulation, all the follicles grow under the action of FSH, only the selected follicles and with the faster growth are taken. However during this stimulation, other smaller follicles a...
Detailed Description
Ovarian stimulation is an essential prerequisite for any in vitro fertilization attempt (IVF) to optimize the chances of delivery per cycle. These depend in the first place on the age of the patients ...
Eligibility Criteria
Inclusion
- Women from 20 to 41 years old
- CFA \<5 and / or AMH \<1, 2 ng / ml
- 19 ≤ BMI ≤ 32
- Supports IVF or ICSI
- If antecedent IVF / ICSI, number of oocytes collected \<4
- Attack rank (puncture with transfer) \<3
- Affiliation to the general social security scheme and benefiting from 100% infertility
Exclusion
- Confirmed ovarian insufficiency (amenorrhea)
- FSH\> 20 IU / l or CFA \<1
- Puncture rank\> 3
- Azoospermia or cryptozoospermia
- Against indication to ovarian stimulation
- Presence of a cyst of indeterminate etiology, ovarian, uterine or mammary carcinoma, hypothalamic or pituitary tumors
- Hypersensitivity to any of the medicines in the protocol
- Moderate or severe pathology of renal or hepatic function
- Evolutionary thromboembolic accidents
Key Trial Info
Start Date :
September 3 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 24 2021
Estimated Enrollment :
88 Patients enrolled
Trial Details
Trial ID
NCT03803228
Start Date
September 3 2018
End Date
November 24 2021
Last Update
December 7 2022
Active Locations (4)
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1
Polyclinique Jean Villar
Bruges, France
2
CHI Creteil
Créteil, France, 94000
3
Cabinet Médical Carré Saint Giniez
Marseille, France
4
Polyclinique Saint Roch
Montpellier, France