Status:
UNKNOWN
Efficacy Management and Adherence Evaluation of Diclofenac in the Treatment of Knee Osteoarthritis Pain
Lead Sponsor:
Peking University People's Hospital
Conditions:
To Investigate the Effect of Diclofenac on Pain Control of Knee Osteoarthritis and the Relationship Between Pain Relief and Medicine Adherence
Eligibility:
All Genders
40+ years
Phase:
NA
Brief Summary
To investigate the effect of dichloride on pain control of knee osteoarthritis and the relationship between pain relief and medicine adherence. To evaluate the pain relief rate of patients with differ...
Eligibility Criteria
Inclusion
- According to the OA diagnostic criteria of knee joint, the side with higher WOMAC score is defined as observing knee joint for patients with both knees conforming to OA diagnostic criteria.
- Repeated knee pain in the past month
- X-ray showed narrowing of articular space, subchondral sclerosis and/or cystic degeneration, and formation of osteophyte at articular margin.
- Joint fluid (\> 2 times) is cool and sticky, WBC \< 2000/ml
- Age over 40
- Morning stiffness less than 30 minutes
- Bone fricative (sensation) during exercise According to 1+2 or 1+3+5+6 or 1+4+5+6, OA of knee joint can be diagnosed.
- The informed consent has been signed
Exclusion
- (1) Joint pain caused by other causes (infection, hip, lumbar and other diseases) (2) Secondary arthritis (rheumatoid arthritis, ankylosing spondylitis, etc.) (3) Severe internal medical complications and other inability to participate in the research (4) Pain in other parts exceeds joint pain (5) Contraindications to diclofenac use: active peptic ulcer/allergy/induced asthma (6) Assessment may not complete the study
Key Trial Info
Start Date :
January 15 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 15 2019
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT03806205
Start Date
January 15 2019
End Date
March 15 2019
Last Update
January 16 2019
Active Locations (1)
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1
Peking University People's Hospital
Beijing, Xicheng District, China, 100044