Status:

COMPLETED

MMP-9 Expression in Permanent Mature Teeth With Symptomatic Pulpitis

Lead Sponsor:

Eglė Gvazdaitytė

Conditions:

Pulpitis

Eligibility:

All Genders

14-33 years

Phase:

NA

Brief Summary

Matrix metallopeptidase-9 (MMP-9) expression was compared in healthy and inflamed pulp and the outcome of coronal pulpotomy in teeth with symptomatic pulpitis was assessed. After procedure blood sampl...

Detailed Description

Introduction: Widely used diagnostic tests do not provide information to distinguish the pulp inflammation stage while improvement of materials, techniques and vital pulp therapy have received a wider...

Eligibility Criteria

Inclusion

  • Teeth diagnosed with symptomatic pulpitis
  • Patients who did not use any NSAIDs before the treatment
  • Positive cold test of investigated teeth
  • Clinically dental caries in contact with pulp chamber
  • Permanent teeth with radiographically closed root apex

Exclusion

  • Patients who refuse to participate in the study
  • Medically compromised patients (with immunosuppressive/systemic diseases, patients on medications)
  • Teeth with periapical radiolucency or clinical signs of apical periodontitis
  • Periodontological compromised teeth (probing depth ≥4mm)
  • Internal/external root resorption in periapical radiograph
  • Pulp chamber and/or root canal calcification in periapical radiograph
  • Teeth with unrestorable crown
  • Teeth with a negative response to cold test

Key Trial Info

Start Date :

March 27 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 11 2018

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT03807674

Start Date

March 27 2017

End Date

February 11 2018

Last Update

January 17 2019

Active Locations (1)

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Lithuanian University of Health Science

Kaunas, Lithuania