Status:
COMPLETED
Effects of Nitroglycerin Versus Labetalol on Tissue Perfusion During Deliberate Hypotension
Lead Sponsor:
Cairo University
Conditions:
Tissue Perfusion
Deliberate Hypotension
Eligibility:
All Genders
18-45 years
Phase:
PHASE4
Brief Summary
Deliberate hypotension is used to provide bloodless field during endoscopic sinus surgery; however, hypotension might impair perfusion of vital organs. The aim of this work is to compare the impact of...
Detailed Description
Hypotensive anesthesia is associated with the risk of reduced tissue perfusion. The usual target mean arterial pressure during deliberate hypotension is 50- 65 mmHg; however, the status of peripheral ...
Eligibility Criteria
Inclusion
- Adult male or female patients
- 18-45 years
- ASA physical status I-II
- scheduled for FESS operations
Exclusion
- uncontrolled hypertension
- cerebrovascular disorders
- coagulation disorders
- cardiovascular diseases
- renal impairment
- liver impairment
- history of allergic reaction to any of the study medications
Key Trial Info
Start Date :
January 19 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 25 2019
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT03809065
Start Date
January 19 2019
End Date
May 25 2019
Last Update
April 27 2020
Active Locations (1)
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1
Kasr Al Ainy
Cairo, Egypt, 11562