Status:

UNKNOWN

Optical Coherence Tomography Guided Percutaneous Coronary Intervention for Drug-eluting In-stent Restenosis

Lead Sponsor:

Chinese PLA General Hospital

Conditions:

CHD - Coronary Heart Disease

Percutaneous Coronary Intervention

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This study is a prospective, registry trial aimed to compare the clinical and angiographic outcomes of OCT-guided and angiography-guided PCI in patients with coronary DES-ISR.

Eligibility Criteria

Inclusion

  • Age 18 years or older
  • Patients with angina or evidence of myocardial ischaemia
  • Patients with restenotic lesions in a previously DES area of a coronary artery
  • Patients suitable to receive any types of percutaneous coronary intervention (including balloon angioplasty and stent implantation)
  • The stent diameter of DES-ISR is 2.5mm to 4.0mm
  • Target lesion length \< 30mm
  • Target lesion stenosis ≥ 70% diameter stenosis on visual assessment, or ≥ 50% diameter stenosis and with evidence of myocardial ischaemia ischemic

Exclusion

  • Patients with acute myocardial infarction with 1 week
  • Patients with evidence of extensive thrombosis in the target vessel
  • Patients with left main coronary artery disease
  • Patients with cardiogenic shock, left ventricular ejection fraction \< 40%,significant renal dysfunction and severe heart valve disease
  • Patients who had cerebral stroke within 6 months before PCI
  • Patients with a life expectancy \< 1 year
  • Patients not able to adhere to follow-up visits

Key Trial Info

Start Date :

March 1 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2020

Estimated Enrollment :

240 Patients enrolled

Trial Details

Trial ID

NCT03809754

Start Date

March 1 2019

End Date

September 1 2020

Last Update

January 23 2019

Active Locations (1)

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Yundai Chen

Beijing, China