Status:
UNKNOWN
Does LAH May Improve the Pregnancy Outcomes?
Lead Sponsor:
Tang-Du Hospital
Conditions:
Pregnancy Outcomes
Eligibility:
FEMALE
22-45 years
Phase:
NA
Brief Summary
A defect in the hatching stage is considered an important cause of implantation failure. Therefore, assisted hatching (AH), which involves artificial disruption of the zona pellucida, has been propose...
Detailed Description
Hatching is a very important process for successful implantation involving the breaking of the embryo out of the zona pellucida at the blastocyst stage. Inadequate hatching of the blastocyst might lea...
Eligibility Criteria
Inclusion
- Patients undergoing IVF/ICSI-ET cycle；
- The zone pellucida of the cleavage-stage embryo is thicker than 8 μm.
Exclusion
- Number of embryos transferred per cycle \>2;
- The transferred embryos including fresh and frozen cycle in the same cycle;
- Embryos developed from the frozen-thawed oocytes.
Key Trial Info
Start Date :
December 26 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
November 1 2019
Estimated Enrollment :
1200 Patients enrolled
Trial Details
Trial ID
NCT03810157
Start Date
December 26 2018
End Date
November 1 2019
Last Update
June 25 2019
Active Locations (1)
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1
Tangdu Hospital
Xi'an, Shaanxi, China, 710038