Status:
RECRUITING
Pencil Beam Scanning in Patients With Renal Tumors
Lead Sponsor:
Children's Hospital of Philadelphia
Conditions:
Renal Tumor
Wilms Tumor
Eligibility:
All Genders
Up to 30 years
Phase:
EARLY_PHASE1
Brief Summary
This is a pilot study to assess acute toxicity in patients receiving flank irradiation using proton therapy for renal tumors.
Detailed Description
Patients with renal tumors including Wilms and clear cell sarcoma of the kidney (CCSK) are treated with multimodality therapy which may include surgery, chemotherapy, and radiation. While long-term di...
Eligibility Criteria
Inclusion
- Less than 30 years of age
- Diagnosis
- a. Any patient with Wilms tumor or clear cell sarcoma of the kidney who would require radiation therapy as standard of care including
- Any patient with favorable histology (FH), stage III disease
- Any patient with focal or diffuse anaplasia
- Any patient with CCSK
- The patient is a candidate for external beam radiotherapy based on standard of care for treatment of Wilms tumor or CCSK
Exclusion
- Prior radiotherapy to the region of the study cancer
- Chemotherapy administered for diagnosis of Wilms tumor or CCSK
- Pregnant or breastfeeding
Key Trial Info
Start Date :
December 26 2017
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 30 2027
Estimated Enrollment :
28 Patients enrolled
Trial Details
Trial ID
NCT03810651
Start Date
December 26 2017
End Date
October 30 2027
Last Update
April 27 2025
Active Locations (1)
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1
Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, United States, 19104