Status:
UNKNOWN
Biobehavioral Correlates of Acute Phobic Fear
Lead Sponsor:
University of Colorado, Boulder
Conditions:
Phobia
Eligibility:
All Genders
18-40 years
Brief Summary
This study seeks to measure the time course of circulating proinflammatory markers (interleukin-1 beta \[IL-1β\], interleukin-6 \[IL-6\], tumor necrosis factor alpha \[TNF-α\], and C-reactive protein ...
Eligibility Criteria
Inclusion
- 18 - 40 years old
- Phobic or nonphobic fear of spiders.
- Willing to proceed through 5-stimulus fear hierarchy or maintain 7 or higher subjective units of distress through fear task (see Procedures section).
Exclusion
- Lifetime history of serious mental illness
- Lifetime history of intellectual or developmental delays
- Lifetime history of chronic physical or medical illness including blood clotting disorders
- Lifetime history of allergies to latex
- Lifetime history of hormonal replacement therapy
- Lifetime history of blindness
- Lifetime history of blood/injection phobia or aversion to needles/injection (based on IPS-Anx and MQ)
- Substance abuse in the past 2 years
- Cigarette/tobacco use in the past 2 years
- Major depression within the past 12 months
- Traumatic stress within the past 12 months
- Pregnancy within the past 12 months
- Anesthesia within the past 3 months
- Night shift work within the past month
- Use of medication within the past month (except for oral contraception)
- Acute illness or infection within the past month
- Average sleep outside of 6 - 10 hours per night within the past month
- Average intake of 4 or more alcoholic beverages per week
- Average intake of 6 or more cups caffeine per day
- Use of marijuana within the week before the laboratory session
- Use of alcohol within the week before the laboratory session
- Body mass index outside of 18.5 - 24.9 range
Key Trial Info
Start Date :
February 4 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 1 2019
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT03813823
Start Date
February 4 2019
End Date
August 1 2019
Last Update
January 23 2019
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.