Status:

COMPLETED

A Novel Formulation of Bifidobacterium Longum BB536 and Lactobacillus Rhamnosus HN001 With Vitamin B6 on IBS Patients

Lead Sponsor:

University of Bari

Conditions:

Irritable Bowel Syndrome

Eligibility:

All Genders

18-70 years

Phase:

PHASE3

Brief Summary

Irritable bowel syndrome (IBS) is one of the most frequent functional gastrointestinal disorder with a prevalence ranging from 10 to 15 percent. IBS results from an interaction among several factors, ...

Detailed Description

Irritable bowel syndrome (IBS) is one of the most frequent functional gastrointestinal disorder with a prevalence ranging from 10 to 15 percent. It is characterized by recurrent chronic abdominal pain...

Eligibility Criteria

Inclusion

  • Diagnosis of IBS according to Rome IV Criteria

Exclusion

  • Diagnosis of structural abnormality of the GI tract
  • Inflammatory bowel disorders
  • Biliary duct obstructions
  • Gallstones
  • Abdominal surgery within the previous six months
  • Infective diseases
  • Drug or alcohol abuse
  • Metabolic disturbances
  • Mental illness
  • Concomitant immunological, haematological or neoplastic disease
  • Severe hepatic insufficiency (i.e., Child-Pugh class C)
  • Severe heart failure (NYHA class III-IV)

Key Trial Info

Start Date :

February 1 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 31 2018

Estimated Enrollment :

25 Patients enrolled

Trial Details

Trial ID

NCT03815617

Start Date

February 1 2017

End Date

December 31 2018

Last Update

January 24 2019

Active Locations (1)

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Clinica Medica "A. Murri", Department of Biomedical Sciences & Human Oncology, University of Bari Medical School

Bari, BA, Italy, 70124