Status:
SUSPENDED
Neuromuscular Electrical Stimulation in Critically Ill Patients.
Lead Sponsor:
University of Sao Paulo
Conditions:
Critical Care
Rehabilitation
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
The study will investigate the effects of neuromuscular electrical stimulation (NMES) in critically ill patients. The objective of this study will be investigate the effects of neuromuscular electrica...
Detailed Description
The study will investigate the effects of neuromuscular electrical stimulation (NMES) in critically ill patients. It will be a randomised crossover clinical trial. Thirty-one patients will enrolled. P...
Eligibility Criteria
Inclusion
- All patients that will be admitted to the intensive care unit
- Hemodynamic stability
- Mechanical ventilation.
Exclusion
- In general:
- a. Pregnant women
- b. Brain death
- c. Neuromuscular diseases
- d. Use of pre-existing neuromuscular blocker in the last 24 hours, prior to the study protocol.
- Contraindications for the use of NMES:
- a. Fractures
- b. Burns
- c. Skin lesions
- d. Systemic vascular impairment diseases such as systemic lupus erythematosus, thromboembolic disease, deep vein thrombosis (which was not therapeutically anticoagulated for a time greater than 36 hours)
- e. Lower limb amputations
- f. Cardiac pacemaker,
- g. Thrombocytopenia less than 20,000/mm3
- h. BMI greater than 35 kg/m2
- i. Important lower extremity oedema
- j. Agitation and/or signs of pain during the electrical stimulation.
- Contraindications to begin or continue NMES procedure:
- a. Mean arterial blood pressure less than 65 mmHg
- b. Use of vasopressor \>50% of themaximum dose (dopamine \>12.5 μg/kg per minute; vasopressin \>0.02U/min and norepinephrine \>1 μg/kg per minute),
- c. Heart rate \<50 or \>140bpm
- d. Arrhythmias with hemodynamic consequences
- e. Myocardial ischemia,
- f. Temperature \<34 or \>39oC
- g. Intracranial pressure \>20 cmH2O
- h. Decrease in 10% of SpO2 baseline value or \<88% for more than one minute.
Key Trial Info
Start Date :
November 13 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 29 2021
Estimated Enrollment :
31 Patients enrolled
Trial Details
Trial ID
NCT03815994
Start Date
November 13 2018
End Date
January 29 2021
Last Update
February 5 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Clinics Hospital
Ribeirão Preto, São Paulo, Brazil, 14049-900