Status:

COMPLETED

Prospective Randomized Trial Comparing Corifollitropin-alfa Late Start vs. Corifollitropin-alfa Standard Start in Expected Poor, Normal and High-responders Undergoing IVF

Lead Sponsor:

University of Turin, Italy

Conditions:

Fertility Disorders

Eligibility:

FEMALE

18-43 years

Phase:

NA

Brief Summary

To compare the number of retrieved oocytes in the late start CF-alfa (day 4) versus standard CF-alfa protocols (day 2) in patients undergoing IVF. The primary analysis will be also performed in specif...

Detailed Description

The investigators hypothesize that: 1. CF-alfa late start (day 4) will show comparable efficacy in terms of number of retrieved oocytes versus standard CF-alfa (day 2) protocol. In certain groups of ...

Eligibility Criteria

Inclusion

  • aged 18- 43 years
  • Male or tubal infertility with indication for IVF treatment
  • No PCOS
  • No previous IVF treatments in the past two months
  • No history of previous Ovarian Hyperstimulation Syndrome (OHSS)
  • No previous IVF cycle with more than 30 growing follicles ≥ 11 mm
  • Antral Follicle Count (AFC) \<20
  • No ovarian cyst nor malignant ovarian tumour, breast, uterus or central nervous cancer

Exclusion

  • AMH \< 0.2 ng/ml
  • Età \> 43 anni

Key Trial Info

Start Date :

April 1 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 31 2018

Estimated Enrollment :

113 Patients enrolled

Trial Details

Trial ID

NCT03816670

Start Date

April 1 2017

End Date

December 31 2018

Last Update

January 25 2019

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Physiopathology of Reproduction and IVF Unit, S. Anna Hospital

Torino, Italy, 10126

Prospective Randomized Trial Comparing Corifollitropin-alfa Late Start vs. Corifollitropin-alfa Standard Start in Expected Poor, Normal and High-responders Undergoing IVF | DecenTrialz