Status:
COMPLETED
Fluid Responsiveness in HFNC Patients
Lead Sponsor:
Hospital Universitari Vall d'Hebron Research Institute
Conditions:
Respiratory Insufficiency
Shock, Septic
Eligibility:
All Genders
18+ years
Brief Summary
The plethysmographic variation index (PVi) is a measure of the respiratory-induced variations in the plethysmographic waveform. Interestingly, in mechanically ventilated patients and under certain con...
Detailed Description
STUDY BACKGROUND The plethysmographic variation index (PVi) is a measure of the respiratory-induced variations in the plethysmographic waveform. Interestingly, in mechanically ventilated patients and ...
Eligibility Criteria
Inclusion
- Patients treated with HFNC presenting with circulatory insufficiency defined as the presence of any of the folling signs: 1) hypotension (systolic blood pressure \<90 mm Hg or the need for norepinephrine), 2) oliguria (urine output \<0.5 mL/kg/hr), and 3) cool, mottled extremities.
Exclusion
- Cardiac arrhythmia
- Known intracardiac shunt
- Severe valvular heart disease
- Severe hypoxemia (PaO2/FIO2 \<60 mmHg)
- Left ventricular ejection fraction of \<50%
- Hemodynamic instability during the procedure (defined as the variation in heart rate or blood pressure of \>10% over the 15-min period before starting the protocol) and those with variations in arterial pulse pressure \<13%.
Key Trial Info
Start Date :
January 1 2017
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 30 2019
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT03817996
Start Date
January 1 2017
End Date
April 30 2019
Last Update
August 13 2019
Active Locations (1)
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1
Hospital Universitari Vall d'Hebron
Barcelona, Spain, 08035