Status:

UNKNOWN

Cardiovascular Effects of EVOO in Healthy Reproductive-aged Women

Lead Sponsor:

University of Vermont Medical Center

Conditions:

Hypertension

Vascular Stiffness

Eligibility:

FEMALE

18-40 years

Phase:

NA

Brief Summary

This study aims to compare changes in cardiovascular function and markers of inflammation and metabolic dysfunction in women randomized to treatment with extra virgin olive oil (EVOO) versus those ran...

Detailed Description

Participants will be randomized to receive 45 ml (40 g) of extra virgin olive oil (EVOO) daily for 8 weeks or an identical dose of a control sunflower seed oil low in oleic acid and phenol content. EV...

Eligibility Criteria

Inclusion

  • Women are eligible to participate if they are between the ages of 18 and 40, in good health, with regular menstrual cycles and no prior pregnancies.

Exclusion

  • Routinely take medications or supplements known to affect blood pressure, heart or blood vessel function, or those with anti-inflammatory or antioxidant properties
  • Smoking
  • Pregnancy
  • Other conditions that would impair adherence, such as allergy to olive oil or sunflower oil or difficulty swallowing

Key Trial Info

Start Date :

February 1 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

February 1 2020

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT03820336

Start Date

February 1 2019

End Date

February 1 2020

Last Update

April 17 2019

Active Locations (1)

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University of Vermont Medical Center

Burlington, Vermont, United States, 05401