Status:
COMPLETED
Rheumatoid Arthritis Disease Activity and Sub Clinical Atherosclerosis
Lead Sponsor:
Assiut University
Conditions:
Rheumatoid Arthritis
Eligibility:
All Genders
18+ years
Brief Summary
RA is associated with traditional cerebrovascular risk factors as subclinical atherosclerosis. Chronic inflammation and high disease activity are associated with atherosclerotic burden, higher incide...
Detailed Description
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease characterized by progressive joint destruction, associated with extra-articular manifestations, affecting different internal orga...
Eligibility Criteria
Inclusion
- RA patients fulfilling ACR 2010 classification criteria over the age of 18 who have active RA (either early with symptoms lasting \< 6 months or established disease lasting \> 6 months) .
Exclusion
- Patients who have previously experienced cardiovascular illness, e.g., heart failure, acute coronary syndrome, revascularization, transient ischemic attacks, and cerebrovascular stroke. Patients who have concomitant hepatic or renal diseases, active infections, malignancy, smoking, hypertension, dyslipidemia, obesity, diabetes mellitus, and hyperuricemia. Patients who are receiving anti-TNF-α therapy.
Key Trial Info
Start Date :
April 15 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 1 2021
Estimated Enrollment :
160 Patients enrolled
Trial Details
Trial ID
NCT03821090
Start Date
April 15 2019
End Date
July 1 2021
Last Update
January 25 2023
Active Locations (1)
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1
Assiut university hospital
Asyut, Egypt, 088