Status:
RECRUITING
Sex-Specific Effects of Endocrine Disruption on Aging and Alzheimer's Disease
Lead Sponsor:
Mayo Clinic
Collaborating Sponsors:
National Institute on Aging (NIA)
Conditions:
Alzheimer Disease
Eligibility:
FEMALE
60+ years
Phase:
PHASE4
Brief Summary
The researchers are trying to determine whether ovarian hormones are associated with aging processes and with the risk of developing Alzheimer's disease in women.
Detailed Description
The proposed project will enroll a total of 614 women. Mayo Clinic Rochester Participants: Each women will have 2-3 clinic visits consisting of cognitive testing, tests of physical function, question...
Eligibility Criteria
Inclusion
- Mayo Clinic Rochester-
- Women who previously participated in this study
- Currently aged 60 years and older
- More than six months post chemotherapy or major surgery requiring general anesthesia
- Willing and able to sign informed consent
Exclusion
- Not able to read and speak English
- In hospice
- Claustrophobic
- If undergoing Tau imaging, cannot have QT Prolongation
- Mayo Clinic Jacksonville-
- Inclusion Criteria:
- African American Women
- Currently aged 60 years and older
- More than six months post chemotherapy or major surgery requiring general anesthesia
- Willing and able to sign informed consent
Key Trial Info
Start Date :
June 27 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2030
Estimated Enrollment :
614 Patients enrolled
Trial Details
Trial ID
NCT03821857
Start Date
June 27 2019
End Date
May 1 2030
Last Update
November 24 2025
Active Locations (2)
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1
Mayo Clinic
Jacksonville, Florida, United States, 32224
2
Mayo Clinic
Rochester, Minnesota, United States, 55905