Status:

COMPLETED

Prefontal tDCS in Patients With Disorders of Consciousness: Neurophysiological and Behavioural Outcomes

Lead Sponsor:

University of Liege

Conditions:

Vegetative State

Minimally Conscious State

Eligibility:

All Genders

16-75 years

Phase:

NA

Brief Summary

Non-invasive brain stimulations techniques have recently shown promising results in patients with disorders. Notably, transcranial direct current stimulation (tDCS) applied over the left dorsolateral ...

Detailed Description

Currently, therapeutic options for severely brain-injured patients with disorders of consciousness (DOC), including patients in unresponsive wakefulness syndrome (UWS) and minimally conscious state (M...

Eligibility Criteria

Inclusion

  • post-comatose patients
  • patients in vegetative state/unresponsive wakefulness syndrome or in minimally conscious state
  • patients with stable condition
  • patients free of sedative drugs and Na+ or Ca++ blockers (e.g., carbamazepine) or NMDA receptor antagonist (e.g., dextromethorphan)

Exclusion

  • premorbid neurology antecedent
  • patients in coma
  • patients \< 28 days after the acute brain injury
  • patients with a metallic cerebral implant/a shunt
  • cranioplasty

Key Trial Info

Start Date :

January 1 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2019

Estimated Enrollment :

15 Patients enrolled

Trial Details

Trial ID

NCT03823508

Start Date

January 1 2018

End Date

June 1 2019

Last Update

July 17 2019

Active Locations (1)

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1

University Hospital of Liege

Liège, Belgium, 4000