Status:

COMPLETED

The Clinical Value of Chromoendoscopy as Surveillance Strategy for Dysplasia Detection in Ulcerative Colitis

Lead Sponsor:

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Conditions:

Ulcerative Colitis

Chromoendoscopy

Eligibility:

All Genders

18+ years

Brief Summary

A recent multicentre randomised controlled trial compared autofluorescence imaging (AFI) with CE for dysplasia detection in colonoscopy surveillance of patients with longstanding UC (FIND-UC). In this...

Eligibility Criteria

Inclusion

  • Patients are eligible for inclusion in this study when they meet the following criteria:
  • Inclusion criteria
  • In order to be eligible to participate in this study, a subject must meet all of the following criteria:
  • \- Patients that where included in the previous FIND-UC trial
  • Exclusion criteria
  • A potential subject who meets any of the following criteria will be excluded from participation in this study:
  • Patients who not receive their surveillance colonoscopy with CE
  • Patients who not undergo their surveillance colonoscopy within 3 months of the surveillance recommendations
  • Withdrawal of individual subjects
  • A patient will be excluded from the study if any of the following events occur:
  • Withdrawal of informed consent
  • The patient requests to be discontinued from the study
  • The bowel preparation is scored as Boston Bowel Preparation Scale \<6
  • Incomplete colonoscopy because the endoscopist is unable to intubate the cecum during the colonoscopy
  • The Mayo-score \> 1 in at least in one of the bowel segments

Exclusion

    Key Trial Info

    Start Date :

    May 9 2016

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    October 1 2018

    Estimated Enrollment :

    210 Patients enrolled

    Trial Details

    Trial ID

    NCT03824418

    Start Date

    May 9 2016

    End Date

    October 1 2018

    Last Update

    January 31 2019

    Active Locations (1)

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    Academic Medical Centre

    Amsterdam, North Holland, Netherlands, 1105AZ