Status:
COMPLETED
High Definition Endoscopy With NBI. Contribution in Patients With Non-erosive Esophagitis
Lead Sponsor:
University of Sao Paulo General Hospital
Collaborating Sponsors:
University of Sao Paulo
Conditions:
GERD
Eligibility:
All Genders
18-70 years
Brief Summary
Most patients with symptomatic gastroesophageal reflux disease (GERD) have a normal upper gastrointestinal endoscopy. Attempts have been made to define new endoscopic techniques for identification of ...
Detailed Description
In this study the investigators focused the attention on patients with symptomatic GERD according to inclusion criteria and used high definition endoscopy with NBI in an attempt to increase the possib...
Eligibility Criteria
Inclusion
- Outpatients aged 18 to 70 years
- Patients with symptoms typical of GERD, on at least two different days over a week, for a period of at least three consecutive months, and with conventional upper gastrointestinal endoscopy (UGE) without oesophageal changes, performed in the last 12 months.
Exclusion
- Hiatal hérnia
- Ulcers of the upper digestive tract
- Drugs that interfere with the physiology of the esophagus
- Esophago-gastric surgeries
- Achalasia of the esophagus
- Esophagitis (erosive, eosinophilic, medicinal, infectious, non-erosive to conventional endoscopy)
- Esophageal stricture
- Esophageal varices
- Clinical situations that prevent more detailed evaluation of the Escamo-colunar junction during endoscopy (psychomotor-agitation, cough)
- Barrett's Esophagus
- Esophageal diverticulum
- Atrophic gastritis
- Recent use of anti-inflammatories \<30 days
- Systemic inflammatory / immune systemic diseases of the gastrointestinal tract
- Recent Infectious Diseases \<30 days
- BMI (Body Mass Index) \> 30 kg / m2
- Pregnant women
- Smoking
- Recent use of anticoagulants
- Comorbidities that may interfere with esophageal motility
- Recent use of PPI (Proton Pump Inhibitor) \<7 days.
Key Trial Info
Start Date :
January 23 2014
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 20 2018
Estimated Enrollment :
70 Patients enrolled
Trial Details
Trial ID
NCT03824431
Start Date
January 23 2014
End Date
November 20 2018
Last Update
February 15 2019
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