Status:

COMPLETED

18F-FSPG PET/CT in Diagnosing Early Lung Cancer in Patients With Lung Nodules

Lead Sponsor:

Andrei Iagaru

Collaborating Sponsors:

Canary Foundation

Boston University

Conditions:

Cigarette Smoker

Current Smoker

Eligibility:

All Genders

45+ years

Phase:

PHASE2

Brief Summary

This phase II trial studies how well 18F-FSPG positron emission tomography (PET)/computed tomography (CT) work in diagnosing early lung cancer in patients with indeterminate lung nodules. PET imaging ...

Detailed Description

PRIMARY OBJECTIVES: I. Comparison of fluorine F 18 L-glutamate derivative BAY94-9392 (18F-FSPG) accumulation with fludeoxyglucose F-18 (18F-FDG) accumulation to assess whether (4S)-4-(3-18F-Fluoropro...

Eligibility Criteria

Inclusion

  • Pulmonary nodule between the size of 7 to 30 mm. Subjects with multiple nodules may be eligible if the dominant nodule is 7 to 30 mm
  • Undergoing standard of care 18F-FDG PET imaging (for indeterminate pulmonary nodule)
  • Current or former cigarette smoker, with \>= 20 pack years
  • Documented informed consent

Exclusion

  • History or previous diagnosis of lung cancer
  • Cancer diagnosis within the last 5 years
  • Pregnant or nursing

Key Trial Info

Start Date :

February 4 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 30 2021

Estimated Enrollment :

15 Patients enrolled

Trial Details

Trial ID

NCT03824535

Start Date

February 4 2019

End Date

July 30 2021

Last Update

April 9 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Stanford Cancer Institute Palo Alto

Palo Alto, California, United States, 94304