Status:
COMPLETED
QL Block With Exparel in Colectomy
Lead Sponsor:
Duke University
Collaborating Sponsors:
Pacira Pharmaceuticals, Inc
Conditions:
Laparotomy
Colectomy
Eligibility:
All Genders
18-85 years
Phase:
PHASE4
Brief Summary
The purpose of this study is to determine if using a different type of injection of local anesthestic (pain medicine) in between the muscle layers of the abdominal wall (called a quadratus lumborum bl...
Detailed Description
Participants in this study will receive exparel via an abdominal muscle nerve block procedure immediately prior to their operation. Participants will be in this study for 96 hours following surgery, w...
Eligibility Criteria
Inclusion
- Patients scheduled for elective, laparoscopic colonic resection by one of three surgeons: Drs. Thacker, Mantyh or Migaly. These surgeons perform this procedure in the same manner
- Age 18-85 years
- American Society of Anesthesiologists (ASA) Physical Class I-III
- BMI 18-35 kg/m\^2
Exclusion
- Inability to consent
- Inability to speak English
- Pregnancy
- Emergency surgery
- Contraindications to regional blockade: coagulopathy or bleeding diathesis, local infection, allergy to local anesthetics
- Allergies/intolerances/contraindications to any of the multimodal agents (acetaminophen, gabapentin, ketorolac)
- Daily opioid equivalent use of 30 mg of morphine or greater at time of consent
- History of drug or alcohol abuse
- Rheumatoid arthritis
- Uncontrolled anxiety, schizophrenia or other psychiatric disorder that, in the opinion of the investigator, may interfere with the study assessments of compliance
Key Trial Info
Start Date :
October 31 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 9 2022
Estimated Enrollment :
35 Patients enrolled
Trial Details
Trial ID
NCT03827291
Start Date
October 31 2019
End Date
December 9 2022
Last Update
October 16 2025
Active Locations (1)
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1
Duke University Medical Center
Durham, North Carolina, United States, 27710