Status:
COMPLETED
Role of Cryobiopsy in Diagnosis of Pleural Effusion
Lead Sponsor:
Assiut University
Conditions:
Pleural Effusion
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
The purpose of this study is to evaluate the feasibility, size and quality of the specimens obtained by cryoprobe in comparison to those specimens obtained by flexible forceps during medical thoracosc...
Detailed Description
* Medical thoracoscopy with single-port-of-entry technique will be performed in the bronchoscopy unit under local anesthesia and conscious sedation using midazolam (2 mg) or pethidin. * vertical incis...
Eligibility Criteria
Inclusion
- \- 1. Unilateral moderate or massive exudative pleural effusion patients. 2. Undiagnosed pleural effusion after simple pleural fluid aspiration, cytology or blind (closed) pleural biopsy using Abram's needle.
- 3\. Age\>18 years old
Exclusion
- Transudative pleural effusion.
- Exudative pleural effusion less than one third of hemithorax.
- Presence of hemorrhagic diathesis (prothrombin concentration \<50% and platelet count \<80,000/mm 3).
- Poor performance state (ECOG performance status \>4) as recommended in BTS (British thoracic society) guidelines 2010.
- Sever uncontrollable cough, hypercapnia and sever respiratory distress.
- Fibrothorax, excessive pleural adhesion.
- \-
Key Trial Info
Start Date :
March 10 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 10 2021
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT03828903
Start Date
March 10 2020
End Date
October 10 2021
Last Update
December 9 2021
Active Locations (2)
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1
Assuit University hospital
Asyut, Egypt, 71511
2
Alaa Salah Abdel gany
Asyut, Egypt