Status:
COMPLETED
8-Hydroxy-2-Deoxyguanosine ,Total Antioxidant Capacity in Oral Premalignant and Malignant Lesions
Lead Sponsor:
Fayoum University
Conditions:
Premalignant Lesion
Eligibility:
All Genders
35-63 years
Brief Summary
Objectives: Investigating the level of salivary 8-hydroxy-2-deoxyguanosine (8-OHdG) and total antioxidant capacity (TAC) in oral premalignant and malignant lesions in order to determine their diagnost...
Detailed Description
Detection of molecular markers in saliva is superior to their detection in serum and other body fluids due to the fact of being an easy non-invasive tool requiring no training for its collection. Cons...
Eligibility Criteria
Inclusion
- All included individuals were not under any current medication, suffering from any systemic condition or having any other oral mucosal disorder.
Exclusion
- Pregnant or lactating females
- subjects having systemic disorder or taking medications;
- subjects who suffer from any other mucosal lesions.
- severe periodontal inflammation
Key Trial Info
Start Date :
April 1 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2018
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT03830710
Start Date
April 1 2018
End Date
December 1 2018
Last Update
February 20 2019
Active Locations (1)
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1
Sandy hassan shaaban
Cairo, Egypt