Status:
COMPLETED
The Impact of Coronary Chronic Total Occlusion Percutaneous Coronary Intervention on Culprit Vessel Physiology
Lead Sponsor:
Mid and South Essex NHS Foundation Trust
Collaborating Sponsors:
Brighton and Sussex University Hospitals NHS Trust
Conditions:
Chronic Total Occlusion of Coronary Artery
Eligibility:
All Genders
18+ years
Brief Summary
Following successful CTO PCI, a multitude of physiological and anatomical changes take place. Contemporary techniques such as dissection/re-entry or lumen-lumen wiring may influence the immediate and ...
Detailed Description
Following successful chronic total occlusion (CTO) percutaneous coronary intervention (PCI), a multitude of physiological and anatomical changes take place. Contemporary techniques such as dissection/...
Eligibility Criteria
Inclusion
- 18 years of age
- Presence of a coronary chronic total occlusion (CTO) scheduled for elective percutaneous coronary angioplasty (PCI)
- Evidence of viability in the CTO Territory
Exclusion
- \< 18 year of age
- Unable to give informed consent
- Known severe chronic kidney disease (creatinine clearance ≤30 mL/min), unless the patient is on dialysis
- Unable to receive antiplatelets or periprocedural anticoagulation
- Contraindications to adenosine
- Any study lesion characteristic resulting in the expected inability to deliver FD-OCT catheter at the distal vessel post CTO PCI (e.g. moderate or severe vessel calcification or tortuosity)
- Pregnancy, planning pregnancy during study period, or breastfeeding
Key Trial Info
Start Date :
January 23 2015
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 1 2018
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT03830853
Start Date
January 23 2015
End Date
January 1 2018
Last Update
December 21 2021
Active Locations (1)
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1
The Essex Cardiothoracic Centre
Basildon, Essex, United Kingdom, S16 5NL