Status:
COMPLETED
Inflammation-mediated Coronary Plaque Vulnerability, Myocardial Viability and Ventricular Remodeling
Lead Sponsor:
Cardio Med Medical Center
Collaborating Sponsors:
George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu Mures
Tîrgu Mureș Emergency Clinical County Hospital, Romania
Conditions:
Acute Myocardial Infarction
Heart Failure
Eligibility:
All Genders
18+ years
Brief Summary
VIABILITY study aims to investigate the link between systemic inflammation, pancoronary plaque vulnerability (referring to the plaque vulnerability within the entire coronary tree), myocardial viabili...
Detailed Description
Patients with acute myocardial infarction (AMI) who survive the acute event, very often present a significant deterioration of their clinical status with progression towards heart failure, which is di...
Eligibility Criteria
Inclusion
- Patients with ST-segment elevation acute myocardial infarction treated by primary PCI within the first 12 hours after the onset of symptoms
- Ability to provide informed consent;
- Patients aged at least 18 years;
Exclusion
- Patients with acute coronary syndrome in the last 30 days
- Unwillingness or incapacity to provide informed consent;
- Allergy to contrast media;
- Absolute or relative contraindications to magnetic resonance imaging
- Pregnancy or lactation;
- Women with childbearing potential in absence of any contraceptive treatment
- Renal insufficiency (creatinine greater than 1.5 mg/dL) or renal failure requiring dialysis;
- Active malignancy or malignancy within the last 5 year prior to enrollment;
- Conditions associated with an estimated life expectancy of under 1 year;
Key Trial Info
Start Date :
July 25 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 1 2022
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT03830944
Start Date
July 25 2019
End Date
March 1 2022
Last Update
August 2 2022
Active Locations (1)
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1
Cardio Med Medical Center
Târgu Mureş, Mureș County, Romania, 540102