Status:
UNKNOWN
Effect of Different Intravenous Fluids on Post-operative Chronic Subdural Hematoma Size and Recurrence
Lead Sponsor:
Carilion Clinic
Conditions:
Chronic Subdural Hematoma
Eligibility:
All Genders
18-65 years
Brief Summary
This study aims to reduce the recurrence rate of chronic subdural hematomas (CSDH) by manipulating the post-operative intravenous fluid use. The hypothesis relies on the relationship between osmolalit...
Detailed Description
Chronic subdural hematoma (CSDH) is a neurological disease characterized by a collection of fluid, blood, and blood degradation matter between the arachnoid and dura mater in a well-developed membrane...
Eligibility Criteria
Inclusion
- Diagnosis of chronic subdural hematoma (based on imaging)
- Need for surgical intervention (assessed by attending neurosurgeon based on full neurological assessment)
- The procedure of choice is burr hole drainage
- Cessation of anti-coagulant therapy with accompanying normal lab values in appropriate time frames respective to the drug
- Tolerance of supine position
Exclusion
- \<60 years old
- Presence of acute hemorrhage, stroke, or parenchymal damage
- Neurological deficits not accountable to mass effect
- Hyponatremia or inherent electrolyte imbalances
- Pregnancy or non-consentable patients
- Previous neurological surgery up to 1 year before being considered for the study
- Rapid re-expansion of brain observed intraoperatively by attending neurosurgeon
- Congestive heart failure or other medical conditions precluding normal postoperative administration of IV fluids
- Blood glucose levels \> 135 mg/dL
Key Trial Info
Start Date :
January 17 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 1 2022
Estimated Enrollment :
35 Patients enrolled
Trial Details
Trial ID
NCT03831997
Start Date
January 17 2019
End Date
June 1 2022
Last Update
October 8 2020
Active Locations (1)
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1
Carilion Roanoke Memorial Hospital
Roanoke, Virginia, United States, 24016