Status:
COMPLETED
Use of Transient Elastogaphy to Assess Diaphragm Function in Mechanically Ventilated Patients
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Conditions:
Ventilator Weaning
Intensive Care Unit
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Mechanical ventilation is a life-saving treatment that can be associated with diaphragm dysfunction, a potentially deleterious acquired disability. It may be the consequence of disuse - under mechanic...
Detailed Description
Objective : The main objective is to correlate ultrasound indices (thickness, thickening, rigidity) to the measurement of transdiaphragmatic pressure in the evaluation of the diaphragmatic function o...
Eligibility Criteria
Inclusion
- All patients receiving mechanical ventilation and having spontaneous efforts will be eligible if they meet the following criteria:
- Inclusion criteria
- Age ≥ 18 years old
- Intubation and mechanical ventilation since 24 hours
- Failure to a first ventilator liberating trial
- nasogastric feeding tube in place
- readiness criteria to undertake a ventilator liberating trial (Boles et al. ERJ 2007)
- patient written consent or next of kin written consent in case of physical inability of the patient to sign the consent form
- french social Health Service registration
- Exclusion criteria
- pregnancy
- protective administrative control
- patient's refusal
- contra indications to the insertion of esophageal and gastric balloons
- allergy to topical anesthetic
- impossible weaning (full dependance to mechanical ventilation)
Exclusion
Key Trial Info
Start Date :
February 14 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 9 2020
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT03832231
Start Date
February 14 2019
End Date
July 9 2020
Last Update
March 1 2021
Active Locations (1)
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1
Groupe Hospitalier Pitié-Salpétrière
Paris, France, 75013