Status:
COMPLETED
Thrombin Generation as a New Test for Anticoagulation Management in Patients With ECMO
Lead Sponsor:
University Hospital, Strasbourg, France
Conditions:
Implantation of a Veno-arterial or Veno-venous ECMO
Eligibility:
All Genders
18+ years
Brief Summary
ECMO (Extracorporeal Membrane Oxygenation) is a circulatory assistance device aiming at maintaining or restoring cardiopulmonary circulation. Complications of this device are mainly hemorrhagic, relat...
Eligibility Criteria
Inclusion
- Male or female age ≥ 18 years old
- Implantation of a veno-arterial or veno-venous ECMO during hospitalization in intensive care
- Informed consent
Exclusion
- Patient on veno-arterial ECMO after cardiac, cardiopulmonary surgery or after insertion of a left or biventricular cardiac assist device
- Contraindication to curative anticoagulation
- Congenital hemostasis disorder or anatomical abnormality predisposing to hemorrhage (hemophilia, constitutional thrombocytopathies, Willebrand disease, hereditary hemorrhagic telangiectasia, etc.)
- History of heparin-induced thrombocytopenia
- Moribund patient at the day of inclusion
- Do Not Resuscitate decision
- Subject under the protection of justice
- Subject under guardianship or curatorship
- Pregnancy
- Breastfeeding
Key Trial Info
Start Date :
May 16 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 1 2021
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT03832842
Start Date
May 16 2019
End Date
February 1 2021
Last Update
February 4 2021
Active Locations (1)
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1
Service de Réanimation médicale CHU Strasbourg
Strasbourg, France, 67091