Status:
UNKNOWN
Moderate Hypofractionated Radiotherapy for Lung Cancer
Lead Sponsor:
North China Petroleum Bureau General Hospital
Conditions:
Lung Cancer
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this study is to evaluate the incidences of Grade III and above radiation-reduced esophagitis and radiation-reduced pneumonia of patients with advanced lung cancer treated with moderate...
Detailed Description
Radiotherapy plays an irreplaceable role in lung cancer. However, due to the long duration of conventional fractionation irradiation, tumor cells will accelerate repopulation after 3 to 4 weeks during...
Eligibility Criteria
Inclusion
- Patients with previously untreated advanced lung cancer were recruited, who were confirmed pathologically or cytologically.
- The Karnofsky performance status (KPS) score ≥60.
- The expected survival time was≥3 months.
- The laboratory examination results showed a neutrophil count ≥2.0 × 109, a hemoglobin level ≥100 g/L, a platelet count ≥100 × 109, and enough liver and kidney functions.
- The patients did not show abnormal electrocardiogram (ECG) results.
- They did not have other combined diseases that required hospitalization.
- Informed consent required before enrollment.
Exclusion
- Patients who were pregnant or breastfeeding.
- Patients who had another malignant tumor history (with the exception of patients with cervical carcinoma in situ and non-malignant melanoma skin cancer that had been clinically cured for at least 5 years), could not receive concurrent chemotherapy due to medical reasons.
- Superior vena cava syndrome.
- Syndrome and severe lung diseases that affected lung function were excluded.
Key Trial Info
Start Date :
November 1 2016
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2025
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT03833193
Start Date
November 1 2016
End Date
March 1 2025
Last Update
March 23 2023
Active Locations (1)
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1
North China Petroleum Bureau General Hospital
Cangzhou, Hebei, China, 062552