Status:
COMPLETED
TDCS for Cocaine Addiction Craving
Lead Sponsor:
Soterix Medical
Collaborating Sponsors:
Icahn School of Medicine at Mount Sinai
Conditions:
Cocaine Use Disorder
Cocaine Dependence
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
Transcranial direct current stimulation (tDCS) is a form of non-invasive brain stimulation in which low level electrical currents are applied to the scalp in order to alter brain function. In the pres...
Detailed Description
The ultimate goal of this project is to develop a portable neuromodulatory intervention to reduce craving in cocaine addiction. This proposed project is in response to NIH/NIDA's solicitation titled "...
Eligibility Criteria
Inclusion
- DSM-5 diagnosis of cocaine use disorder
- Ability to understand the risks/benefits of the study, provide informed consent and perform tasks as per protocol
- English speaking
- For females of childbearing capacity, current use of a medically acceptable form of birth control
Exclusion
- Current or past history of a major neurological disorder (e.g. mental retardation, Parkinson's disease, Lewy body disease, Huntington's disease, MS, ALS, stroke, delirium tremens) or seizures, including those symptoms associated with periods of cocaine withdrawal or abstinence
- History of Axis I disorder, other than substance use disorder, that is associated with psychotic symptoms (e.g. schizophrenia) or neurodevelopmental disorder (e.g., autism)
- Use of medications (current or in the past 6 months) with known CNS effects or which may alter cerebral function, except psychotropics for depression/anxiety/PTSD (e.g. SSRIs)
- Clinically significant unstable medical illness or infection (e.g. HIV, hepatitis, etc.)
- Presence of contraindicated metallic implants or devices which may be impacted by electrical stimulation (e.g. cardiac pacemaker/defibrillator, medication pump, cochlear implant, implanted brain stimulator)
- Head trauma with loss of consciousness for more than 30 minutes
- Pregnancy or breast feeding
Key Trial Info
Start Date :
February 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 30 2019
Estimated Enrollment :
25 Patients enrolled
Trial Details
Trial ID
NCT03833583
Start Date
February 1 2019
End Date
September 30 2019
Last Update
November 18 2024
Active Locations (1)
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1
Icahn School of Medicine at Mount Sinai
New York, New York, United States, 10029