Status:
COMPLETED
The Phenylephrine vs. Norepinephrine Infusion Undergoing Cesarean Section
Lead Sponsor:
China International Neuroscience Institution
Conditions:
Cesarean Section Complications
Eligibility:
FEMALE
20-45 years
Phase:
PHASE2
PHASE3
Brief Summary
Compare 0.05 μg/kg/min Norepinephrine and 0.25 μg/kg/min phenylephrine effect on fetus and parturient during Cesarean Section
Detailed Description
1. Compare 0.05 μg/kg/min Norepinephrine and 0.25 μg/kg/min phenylephrine and control group effect on parturient hemodynamic change (systolic blood pressure SBP, diastolic blood pressure DBP,mean arte...
Eligibility Criteria
Inclusion
- a healthy singleton pregnancy scheduled for elective cesarean delivery (CD) under combined spinal-epidural anesthesia (CSEA),
- American Society of Anesthesiologists (ASA) physical status I/II
- 20 to 40 years old
Exclusion
- history of mental disorder or epilepsy,
- tricyclic or imipramine antidepressant use,
- central nervous system (CNS) disease,
- preexisting or pregnancy-induced hypertension,
- lumbar injury,
- severe hypovolemia,
- allergy
- history of hypersensitivity to vasopressor
- body mass index (BMI) \>40 kg/m2,
- infection at the puncture site
Key Trial Info
Start Date :
February 20 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 2 2019
Estimated Enrollment :
238 Patients enrolled
Trial Details
Trial ID
NCT03833895
Start Date
February 20 2019
End Date
September 2 2019
Last Update
February 10 2020
Active Locations (1)
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1
Xuanwu Hospital
Beijing, Beijing Municipality, China, 100053