Status:

COMPLETED

Characterizing the Impact and Treatment of Reproductive Tract Bleeding on Women and Post-menarchal Girls With Bleeding Disorders

Lead Sponsor:

Oregon Health and Science University

Collaborating Sponsors:

American Thrombosis and Hemostasis Network

Conditions:

Hemophilia A

Bleeding Disorder

Eligibility:

FEMALE

10-65 years

Brief Summary

Characterizing the impact and treatment of reproductive tract bleeding on women and post-menarchal girls with bleeding disorders. Objectives: This is a cross-sectional observational study of women an...

Detailed Description

This is a multi-center, cross-sectional study of women and girls with bleeding disorders receiving care at Hemophilia Treatment Centers (HTCs). To further characterize this population, WG who receive ...

Eligibility Criteria

Inclusion

  • Women and girls with an active diagnosis of a congenital bleeding disorder (as designated by the institution inputting data);
  • Deficiencies of factors VIII, IX, II, V, VII, VII, IX, X, XI, FV+VIII, XIII, Plasminogen Activator Inhibitor 1(PAI-1), hypo-, a-, or dys-fibrinogenemia
  • von Willebrand Disease (Type 1, Type 1c, Type 2A, Type 2B, Type 2M, Type 2N, Type 3, Low VWF)
  • Any platelet function disorder (i.e. Glanzmann Thrombasthenia, Bernard Soulier Syndrome, Platelet Storage Pool disorder, MYH9 disorders, Gray Platelet syndrome, Dense granule deficiency)
  • Ehlers Danlos Syndrome
  • Post-menarchal: has had at least 1 period at the time of study entry
  • Participating in the ATHNdataset

Exclusion

  • Male gender
  • Acquired bleeding disorder
  • Thrombotic disorder
  • Non-English speaking

Key Trial Info

Start Date :

September 5 2018

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

April 1 2022

Estimated Enrollment :

256 Patients enrolled

Trial Details

Trial ID

NCT03834727

Start Date

September 5 2018

End Date

April 1 2022

Last Update

April 18 2023

Active Locations (1)

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Oregon Health and Science University

Portland, Oregon, United States, 97239