Status:
UNKNOWN
Minor Salivary Gland Transplantation for Cicatrizing Conjunctivitis
Lead Sponsor:
National Taiwan University Hospital
Conditions:
Cicatrizing Conjunctivitis
Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum
Eligibility:
All Genders
20-85 years
Phase:
NA
Brief Summary
This is a prospective study that aimed to observe the therapeutic effects of minor salivary gland transplantation for cicatrizing conjunctivitis patients.
Detailed Description
Cicatrizing conjunctivitis can be the common presentation of many ocular surface diseases as Stevens-Johnson syndrome (SJS), mucous membrane pemphigoid (MMP), chemical burn, Sjogren syndrome, chronic ...
Eligibility Criteria
Inclusion
- age 20-85 years old
- unilateral or bilateral cicatrizing conjunctivitis
- severe aqueous deficiency dry eye ( Schirmer I test result of less than 2mm)
- chronic ocular surface disease score (COCS) over 3 points
- Oxford scheme over grade III
Exclusion
- active ocular infection
- active corneal melting
- severe xerostomia (modified Schirmer I test result of less than 25mm)
Key Trial Info
Start Date :
September 1 2016
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2021
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT03839069
Start Date
September 1 2016
End Date
June 1 2021
Last Update
February 15 2019
Active Locations (1)
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1
Department of Ophthalmology, National Taiwan University Hospital
Taipei, Taiwan, 10002