Status:

UNKNOWN

A Prospective Translational Tissue Collection Study in Early and Advanced Pancreatic Ductal Adenocarcinoma and Pancreatic Neuroendocrine Tumours to Enable Further Disease Characterisation and the Development of Potential Predictive and Prognostic Biomarkers

Lead Sponsor:

Royal Marsden NHS Foundation Trust

Conditions:

Pancreatic Adenocarcinoma

Eligibility:

All Genders

18+ years

Brief Summary

There are several types of early pre-cancerous lesions found in the pancreas which have the potential to develop into pancreatic cancer. Although different patients' pancreatic cancers or pre-cancerou...

Detailed Description

The main objective is to describe the incidence and distribution of tumour biomarkers, and to identify molecular subgroups from a multicentre series of patients who are investigated for and subsequent...

Eligibility Criteria

Inclusion

  • Patient is being investigated or treated for pancreatic cancer or precursor lesions at The Royal Marsden Hospital and referring centres during the study period.
  • Patient has a histologically/cytologically confirmed diagnosis of pancreatic ductal adenocarcinoma, or pancreatic neuroendocrine tumour OR Patient has a tissue lesion suspicious for pancreatic cancer amenable to core needle biopsy or surgery and is clinically fit enough to undergo a tumour biopsy or surgery according to investigator assessment and local guidelines.
  • Patient is ≥ 18 years of age.
  • Patient can understand the patient information sheet and is able to provide written informed consent.
  • Patient has sufficient tissue and/or blood and/or urine and/or stool and/or saliva sampling for analysis as per the protocol.

Exclusion

  • 1\. Patients who are not treated at all at The Royal Marsden Hospital or referring centre.

Key Trial Info

Start Date :

January 10 2019

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 10 2023

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT03840460

Start Date

January 10 2019

End Date

January 10 2023

Last Update

February 20 2020

Active Locations (1)

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1

The Royal Marsden NHS Foundation Trust

Sutton, Surrey, United Kingdom, SM2 5PT