Status:

COMPLETED

Effects of Chronic Energy Drink Consumption on Cardiometabolic Endpoints

Lead Sponsor:

University of the Pacific

Conditions:

Cardiovascular Diseases

Eligibility:

All Genders

18-40 years

Phase:

NA

Brief Summary

Many people use energy drinks (EDs) regularly, but the overall health concerns are still unknown. There are many energy drink products that contain a mixture of caffeine and other energy-boosting ingr...

Detailed Description

The popularity of energy drinks (EDs) have increased over the last few decades due to their purported benefits as mental and physical performance enhancements. While caffeine is a major ingredient in ...

Eligibility Criteria

Inclusion

  • Healthy adults aged 18 - 40 years
  • Participants willing to adhere to study drink schedule (28 days)

Exclusion

  • Naïve caffeine consumers (\< 2 cups of coffee \[or equivalent caffeine intake\] per week)
  • Chronic medical conditions including cardiovascular disease (known history of cardiac arrhythmias, family history of premature sudden cardiac death before age 60, cardiomyopathy, atherosclerosis), smoking, renal or hepatic dysfunction
  • Prolonged corrected QT (QTc) interval
  • History of substance abuse, including alcohol
  • Concurrent use of prescription drugs or over-the-counter products that may interact with study drinks (with the exception of oral contraceptives that have been used for over 1 month)
  • Baseline Blood Pressure greater than 140/90 mmHg
  • Baseline fasting blood glucose greater than 126 mg/dL or random blood glucose greater than 200 mg/dL
  • Females only: pregnancy or lactation, or planning to get pregnant within next 28 days

Key Trial Info

Start Date :

March 6 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 30 2020

Estimated Enrollment :

15 Patients enrolled

Trial Details

Trial ID

NCT03840863

Start Date

March 6 2019

End Date

July 30 2020

Last Update

November 6 2020

Active Locations (1)

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1

University of the Pacific

Stockton, California, United States, 95211