Status:
UNKNOWN
Metabolism of Branched-chain Amino Acids in Monocyte/Macrophage During Sepsis
Lead Sponsor:
West China Hospital
Conditions:
Sepsis Syndrome
Eligibility:
All Genders
18-70 years
Brief Summary
The current project was designed to examine the metabolic level of branched-chain amino acids in plasm and monocyte/macrophage, and its role in immune dysfunction during sepsis.
Detailed Description
In this study, the investigators will collect the peripheral blood of 1,3,7,14 day after diagnose of sepsis. Then, the concentration of branched-chain amino acids(BCAAs) in monocytes and plasma, and t...
Eligibility Criteria
Inclusion
- patients diagnosed with sepsis, with or without type 2 diabetes
- healthy volunteers
Exclusion
- patients with immunodeficient diseases
- patients who accept glucocorticoid or immunosuppressant
- patients with an age younger than 18 years
- patients who cannot provide the informed consent
Key Trial Info
Start Date :
February 11 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
February 28 2022
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT03842371
Start Date
February 11 2019
End Date
February 28 2022
Last Update
February 15 2019
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