Status:
COMPLETED
Neurocognitive and Neurobehavioral Mechanisms of Change Following Psychological Treatment for Alcohol Use Disorder
Lead Sponsor:
University of New Mexico
Collaborating Sponsors:
The Mind Research Network
Conditions:
Alcohol Use Disorder
Alcohol Abuse
Eligibility:
All Genders
22-85 years
Phase:
NA
Brief Summary
Alcohol Use Disorder (AUD) is a significant public health problem, with prevalence rates of 13.9% for current and 29.1% for lifetime diagnosis (Grant et al., 2015). AUD creates harm at the individual,...
Detailed Description
Although pharmacological and psychosocial treatments for alcohol use disorders (AUDs) exist that improve outcomes over natural recovery (Finney et al., 2013), outcomes are still modest. Identifying me...
Eligibility Criteria
Inclusion
- Age 22-85 years
- Self-identify as a heavy/binge/weekly drinker
- Engage in "hazardous and harmful alcohol use" (Babor et al., 2001) based on an AUDIT score \> 8 for men and \> 7 for women
- Breath alcohol level of 0.00 at in-person screening
- Right handed
- Explicitly be seeking help for their drinking
- Alcohol use during the past 30 days
Exclusion
- History of brain injury or neurological diagnoses
- Evidence of current psychosis
- Past-year substance dependence other than nicotine or marijuana
- Evidence of recent illicit drug (other than marijuana) use on a urine screen
- Contraindications for MRI (e.g., medical devices in the body)
- Female participants who think they may be pregnant must pass a urine pregnancy screen prior to each MRI scanning session
- Estimated IQ \< 80
- Unable to read or speak English fluently
- History of major alcohol withdrawal
- Currently in treatment for alcohol use (or within the past 6 months)
Key Trial Info
Start Date :
November 14 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 31 2025
Estimated Enrollment :
110 Patients enrolled
Trial Details
Trial ID
NCT03842670
Start Date
November 14 2018
End Date
March 31 2025
Last Update
April 22 2025
Active Locations (2)
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1
The Mind Research Network
Albuquerque, New Mexico, United States, 87106
2
The University of New Mexico
Albuquerque, New Mexico, United States, 87106