Status:
COMPLETED
Weaning Protocol for High Flow Nasal Cannula Oxygen Therapy
Lead Sponsor:
Seoul National University Hospital
Conditions:
High Flow Nasal Cannula
Respiratory Insufficiency
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
High flow nasal cannula oxygen therapy has been widely used in critically ill patients. Despite effectiveness of high flow nasal cannula as a treatment, optimal methods to withdrawal high flow nasal c...
Detailed Description
Comparison of three weaning strategies: flow reduction first versus fraction of inspired oxygen (FiO2) first versus simultaneous reduction
Eligibility Criteria
Inclusion
- The patients applying high flow nasal cannula and satisfying the following weaning criteria.
- Patient who has recovered from the underlying condition
- No signs of respiratory distress like agitation, diaphoresis or anxiety
- Arterial pH ≥ 7.35, SpO2 \> 90% on FiO2 ≤ 0.5
- Respiratory rate ≤ 25/min, Heart rate ≤120/min, Systolic blood pressure ≥ 90mmHg
Exclusion
- Severe hypercapnia (pH \<7.25)
- Respiratory arrest requiring tracheal intubation
- Cardiac arrest, acute coronary syndrome or life threatening arrhythmias
- Failure of more than two organs
- Recent trauma or burns of the neck and face
- Non- cooperation
- Pregnancy
- Refusal of treatment
Key Trial Info
Start Date :
January 24 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 31 2024
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT03845244
Start Date
January 24 2019
End Date
March 31 2024
Last Update
April 18 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Seoul National University Bundang Hospital
Seongnam-si, Gyeonggi-do, South Korea, 13620